High daily doses of metformin IR have to be split up throughout the day. The ADA doesn’t recommend more than 2,550 mg per day of metformin IR. For that reason, your provider may start you at a low dose and then increase it slowly over time.ĭosing for metformin IR usually starts at 500 mg per day and is then increased to 500 mg twice per day, then to 1,000 mg in the morning and 500 mg at night, and finally, to 1,000 mg in the morning and 1,000 mg at night. One of the most common side effects of metformin is upset stomach and diarrhea. Metformin ER is slowly released as it passes through your stomach and breaks apart in your intestines.ĭosing for metformin tends to be adjusted over time based on how you respond. You may notice metformin ER in your stools as a soft white mass after going to the bathroom. Do not crush or chew metformin ER swallow it whole. You can take metformin if you also take other medications. However, I often advise patients to take it with food to prevent stomach aches. Metformin should be taken by mouth and can be taken with or without food. How are metformin and metformin ER taken?
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